Journal article icon

Journal article

T(H)1, T(H)2, and T(H)17 cells instruct monocytes to differentiate into specialized dendritic cell subsets.

Abstract:

Monocytes and T helper (T(H)) cells rapidly infiltrate inflamed tissues where monocytes differentiate into inflammatory dendritic cells (DCs) through undefined mechanisms. Our studies indicate that T(H) cells frequently interact with monocytes in inflamed skin and elicit the differentiation of specialized DC subsets characteristic of these lesions. In psoriasis lesions, T(H)1 and T(H)17 cells interact with monocytes and instruct these cells to differentiate into T(H)1- and T(H)17-promoting DC...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Alonso, MN More by this author
Suhoski, MM More by this author
Expand authors...
Journal:
Blood
Volume:
118
Issue:
12
Pages:
3311-3320
Publication date:
2011-09-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:5b0d89c5-4af6-429c-869b-cc10844e42ce
Source identifiers:
375295
Local pid:
pubs:375295

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP