- Abstract:
-
In this study we characterize a novel gene on human chromosome 9 and its translation product, PC3-secreted microprotein (PSMP). The gene contains three exons that encode a protein of 139 amino acid residues, including a predicted signal peptide of 36 residues. The molecule is homologous to beta-microseminoprotein (MSP), a protein of unknown function, secreted at high concentration by the prostate gland. These two proteins have only 23% sequence identity, but their common origin is revealed by...
Expand abstract - Publisher copy:
- 10.1515/bc.2007.032
-
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- Journal:
- Biological chemistry
- Volume:
- 388
- Issue:
- 3
- Pages:
- 289-295
- Publication date:
- 2007-03-05
- DOI:
- EISSN:
-
1437-4315
- ISSN:
-
1431-6730
- URN:
-
uuid:5af6583c-e5a7-4cb2-8984-34c45b9cf317
- Source identifiers:
-
365947
- Local pid:
- pubs:365947
- Copyright date:
- 2007
Journal article
A highly conserved protein secreted by the prostate cancer cell line PC-3 is expressed in benign and malignant prostate tissue.
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