Journal article icon

Journal article

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.

Abstract:

RATIONALE: Creatine is thought to be involved in the spatial and temporal buffering of ATP in energetic organs such as heart and skeletal muscle. Creatine depletion affects force generation during maximal stimulation, while reduced levels of myocardial creatine are a hallmark of the failing heart, leading to the widely held view that creatine is important at high workloads and under conditions of pathological stress. OBJECTIVE: We therefore hypothesised that the consequences of creatine-defic...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Circulation research
Volume:
112
Issue:
6
Pages:
945-955
Publication date:
2013-03-01
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
Source identifiers:
374250

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP