- Abstract:
-
We examined the timing of apoptosis and the expression of the DNA repair proteins poly(ADP-ribose) polymerase (PARP) and Ku80 in sections of frontal and temporal lobes from patients who had suffered severe brain ischaemia due to a cardiac arrent. In situ end-labelling (ISEL) was used to detect apoptotic cells, and immunohistochemistry to assess PARP and Ku80. ISEL of scattered neurons and glia was demonstrable predominantly during the first 24 h after ischaemia. PARP and Ku80 immunoreactivity...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1097/00001756-199804200-00001
-
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- Journal:
- Neuroreport
- Volume:
- 9
- Issue:
- 6
- Pages:
- 955-959
- Publication date:
- 1998-04-05
- DOI:
- EISSN:
-
1473-558X
- ISSN:
-
0959-4965
- URN:
-
uuid:5ad63119-507a-40f8-b545-23d878d70d2e
- Source identifiers:
-
36188
- Local pid:
- pubs:36188
- Language:
- English
- Keywords:
- Copyright date:
- 1998
Journal article
Apoptosis and expression of DNA repair proteins in ischaemic brain injury in man.
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