- Abstract:
-
A major side effect of aromatase inhibitor (AI) therapy is AI-related arthralgia (AIA), which often leads to therapy discontinuation. We aimed to identify genetic variants associated with AIA and therapy discontinuation in the first year of AI treatment. Our prospective cohort study included 343 postmenopausal women with early breast cancer starting AI therapy. Single nucleotide polymorphisms (SNPs) in candidate genes involved in estrogen and vitamin D signaling were selected. Univariate and ...
Expand abstract - Publisher copy:
- 10.1007/s10549-013-2638-3
-
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- Journal:
- Breast Cancer Research and Treatment
- Volume:
- 140
- Issue:
- 2
- Pages:
- 385-395
- Publication date:
- 2013-07-05
- DOI:
- EISSN:
-
1573-7217
- ISSN:
-
0167-6806
- URN:
-
uuid:5acbcf82-993c-4c55-8003-2eb745cda565
- Source identifiers:
-
419407
- Local pid:
- pubs:419407
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Genetic determinants of aromatase inhibitor-related arthralgia: The B-ABLE cohort study
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