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Host defences to Citrobacter rodentium

Abstract:

Citrobacter rodentium is a natural non-invasive bacterial pathogen which infects the distal colon of mice. It uses the same molecular mechanisms of type III secretion as human enteropathogenic and enterohemorrhagic Escherichia coli to colonise the epithelial cells of the gut and is therefore an ideal model to study host-bacterial pathogen interactions in vivo. Infection elicits mucosal inflammation with similarities to inflammatory bowel disease, and so it is a readily accessible model to inv...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1078/1438-4221-00247

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
St Anne's College
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
International Journal of Medical Microbiology Journal website
Volume:
293
Issue:
1
Pages:
87-93
Publication date:
2004-11-10
DOI:
EISSN:
1618-0607
ISSN:
1438-4221
Pmid:
12755369
Source identifiers:
98265

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