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Direct detection of single molecules by optical absorption

Abstract:

The advent of single molecule optics has had a profound impact in fields ranging from biophysics to material science, photophysics, and quantum optics. However, all existing room-temperature single molecule methods have been based on fluorescence detection of highly efficient emitters. Here we demonstrate that standard, modulation-free measurements known from conventional absorption spectrometers can indeed detect single molecules. We report on quantitative measurements of the absorption cros...

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Physical and Theoretical Chem
Role:
Author
Publication date:
2010-07-20
URN:
uuid:5a9e9f3a-0830-4535-9833-dbc03537bca9
Source identifiers:
118499
Local pid:
pubs:118499

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