Journal article
Crystal structure and functional characterization of the complement regulator mannose-binding lectin (MBL)/ficolin-associated protein-1 (MAP-1).
- Abstract:
-
The human lectin complement pathway activation molecules comprise mannose-binding lectin (MBL) and ficolin-1, -2, and -3 in complex with associated serine proteases MASP-1, -2, and -3 and the non-enzymatic small MBL associated protein or sMAP. Recently, a novel plasma protein named MBL/ficolin-associated protein-1 (MAP-1) was identified in humans. This protein is the result of a differential splicing of the MASP1 gene and includes the major part of the heavy chain but lacks the serine proteas...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 287
- Issue:
- 39
- Pages:
- 32913-32921
- Publication date:
- 2012-09-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
344132
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:344132
- UUID:
-
uuid:5a93f299-b45c-4f79-8a6d-a6ab0cae27a5
- Local pid:
- pubs:344132
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2012
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