Journal article
Directed synthesis of all four pure stereoisomers of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A
- Abstract:
-
The first preparation of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A and its likewise naturally occurring minor atropisomer, in an atropisomerically pure form, is described. The synthesis succeeded by resolution of the already rotationally hindered, and thus atropo-diastereomeric acetamide precursors, which were then, without major loss of stereochemical information, cyclized to the respective target molecules. The strategy was applied to the first synthesis of the regio...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ German Research Foundation
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Grant:
SFB 630: Agents against Infectious Diseases
Bibliographic Details
- Publisher:
- American Chemical Society Publisher's website
- Journal:
- Organic Letters Journal website
- Volume:
- 18
- Issue:
- 24
- Pages:
- 6508-6511
- Publication date:
- 2016-12-01
- Acceptance date:
- 2016-12-01
- DOI:
- EISSN:
-
1523-7052
- ISSN:
-
1523-7060
- Pmid:
-
27978644
- Source identifiers:
-
863175
Item Description
- Language:
- English
- Pubs id:
-
pubs:863175
- UUID:
-
uuid:5a532ddb-e85f-4bc8-bc59-cb3e79d8eb93
- Local pid:
- pubs:863175
- Deposit date:
- 2018-07-05
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2016
- Notes:
- © 2016 American Chemical Society
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