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Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling.

Abstract:

Adrenergic signaling has important roles in synaptic plasticity and metaplasticity. However, the underlying mechanisms of these functions remain poorly understood. We investigated the role of octopamine, the invertebrate counterpart of adrenaline and noradrenaline, in synaptic and behavioral plasticity in Drosophila. We found that an increase in locomotor speed induced by food deprivation was accompanied by an activity- and octopamine-dependent extension of octopaminergic arbors and that the ...

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Publisher copy:
10.1038/nn.2716

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Journal:
Nature neuroscience
Volume:
14
Issue:
2
Pages:
190-199
Publication date:
2011-02-05
DOI:
EISSN:
1546-1726
ISSN:
1097-6256
URN:
uuid:5a4719c8-18a1-44de-848c-250157c539a7
Source identifiers:
237550
Local pid:
pubs:237550

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