Background: A multicenter genome-wide association scan for Crohn's Disease (CD) has recently reported 40 CD susceptibility loci, including 29 novel ones (19 significant and 10 putative). To gain insight into the genetic overlap between CD and ankylosing spondylitis (AS), these markers were tested for association in AS patients. Principal Findings: Two previously established associations, namely with the MHC and IL23R loci, were confirmed. In addition, rs28... Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's version
- Copyright holder:
- Laukens et al.
- Copyright date:
- Copyright © 2010 Laukens et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record