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Early initiation of low-dose atorvastatin treatment after an acute ST-elevated myocardial infarction, decreases inflammatory process and prevents endothelial injury and activation.

Abstract:

BACKGROUND: High-dose statin treatment improves clinical outcome of ST-elevated myocardial infarction (STEMI). However, the effect of low-dose atorvastatin treatment on inflammatory and pro-thrombotic molecules during the post-STEMI period is unclear. We investigated the effect of low-dose atorvastatin treatment on the kinetics of cytokine IL-6, vascular cell adhesion molecule (sVCAM-1) and endothelium-derived markers of thrombosis/fibrinolysis such as von Willebrand factor (vWF), plasminoge...

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Authors


Stefanadi, E More by this author
Tousoulis, D More by this author
Antoniades, C More by this author
Bosinakou, E More by this author
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Journal:
International journal of cardiology
Volume:
133
Issue:
2
Pages:
266-268
Publication date:
2009-04-05
DOI:
EISSN:
1874-1754
ISSN:
0167-5273
URN:
uuid:5a35138a-8697-4521-83d7-1790926d1839
Source identifiers:
223251
Local pid:
pubs:223251

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