The tissue distribution of T lymphocytes expressing different CD45 polypeptides.
The distribution of T lymphocytes expressing the different polypeptides of the leucocyte common antigen (LCA) family detected by CD45R and UCHL1 antibodies has been studied in normal lymphoid tissues. In the thymus most cortical thymocytes express UCHL1 and co-express CD4 and CD8. The more mature membrane CD3+ (mainly medullary) T cells are heterogenous and may express both UCHL1 and CD45R weakly or be restricted to display CD45R or UCHL1 alone. In the medulla both the CD45R+ and UCHL1+ subpo...Expand abstract
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