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Effects of interferon alpha on human osteoprogenitor cell growth and differentiation in vitro.

Abstract:

The specific effects of interferon alpha (IFNalpha), on the differentiation pathways of human osteogenic cells are not known. The aim of this study was to investigate possible effects of IFNalpha on osteogenic development by investigating cell differentiation, colony formation (colony forming unit-fibroblastic, CFU-F), cell proliferation, and gene expression, in particular bone morphogenetic protein (BMP) expression, of human bone marrow osteoprogenitor cells. Human bone marrow fibroblasts we...

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Publication status:
Published

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Authors


Oreffo, RO More by this author
Romberg, S More by this author
Joyner, CJ More by this author
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Journal:
Journal of cellular biochemistry
Volume:
74
Issue:
3
Pages:
372-385
Publication date:
1999-09-05
DOI:
EISSN:
1097-4644
ISSN:
0730-2312
URN:
uuid:59f6e789-4881-4ae4-b8e9-bbb3beb7c5db
Source identifiers:
108698
Local pid:
pubs:108698

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