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Thesis

Understanding degeneration and the capacity for reorganisation in the adult human visual cortex

Abstract:

Stargardt Macular Dystrophy (STGD1) causes degeneration of the photoreceptors, predominantly constrained to the cones within the central retina, which causes a loss of high acuity vision within the central visual field. Due to the topographic organisation of the primary visual cortex (V1), photoreceptor degeneration starting in the central retina projects to a focal region within posterior V1. There are treatments in development that aim to restore loss at the retina, however the majority ...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Research group:
Wellcome Centre for Integrative Neuroimaging
Oxford college:
St John's College
Role:
Author
ORCID:
0000-0001-9139-2246

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Research group:
Wellcome Centre for Integrative Neuroimaging
Oxford college:
New College
Role:
Supervisor
ORCID:
0000-0002-8089-6198
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Research group:
Nuffield Laboratory of Ophthalmology
Oxford college:
Kellogg College
Role:
Supervisor
ORCID:
0000-0001-7373-2665


More from this funder
Grant:
project code: HMT00100 task code: HM00.21
Programme:
DPhil in Clinical Neurosciences


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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