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A single dose of mirtazapine modulates neural responses to emotional faces in healthy people.

Abstract:

RATIONALE: Single-dose administration of selective serotonin and noradrenaline reuptake blockers has been shown to alter emotional processing in both behavioral and fMRI studies in healthy volunteers. Mirtazapine is a clinically established antidepressant with different pharmacological actions from monoamine reuptake inhibitors, involving blockade of noradrenaline α(2)-adrenoceptors and multiple 5-HT receptor subtypes. The aim of this study was to investigate the effect of a single dose of m...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-010-1983-8

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Institution:
University of Oxford
Department:
Oxford
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
Psychopharmacology
Volume:
212
Issue:
4
Pages:
625-634
Publication date:
2010-12-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:59aedad8-31ba-4918-85d2-73c6c81345fd
Source identifiers:
139488
Local pid:
pubs:139488

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