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Induction of the neural crest state: Control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions

Abstract:

Neural crest cells are a population of multipotent stem cell-like progenitors that arise at the neural plate border in vertebrates, migrate extensively, and give rise to diverse derivatives such as melanocytes, craniofacial cartilage and bone, smooth muscle, peripheral and enteric neurons and glia. The neural crest gene regulatory network (NC-GRN) includes a number of key factors that are used reiteratively to control multiple steps in the development of neural crest cells, including the acqu...

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Publisher copy:
10.1016/j.ydbio.2012.03.014

Authors


Prasad, MS More by this author
Sauka-Spengler, T More by this author
LaBonne, C More by this author
Journal:
Developmental Biology
Volume:
366
Issue:
1
Pages:
10-21
Publication date:
2012-06-01
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
URN:
uuid:599c552a-a6ae-4378-9221-30cad6f86fd1
Source identifiers:
334426
Local pid:
pubs:334426

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