Journal article icon

Journal article

Calcineurin B-like domains in the large regulatory alpha/beta subunits of phosphorylase kinase.

Abstract:

Phosphorylase kinase (PhK) is a large hexadecameric complex that catalyzes the phosphorylation and activation of glycogen phosphorylase (GP). It consists in four copies each of a catalytic subunit (gamma) and three regulatory subunits (alpha beta delta). Delta corresponds to endogenous calmodulin, whereas little is known on the molecular architecture of the large alpha and beta subunits, which probably arose from gene duplication. Here, using sensitive methods of sequence analysis, we show th...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/prot.22006

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
Proteins
Volume:
71
Issue:
4
Pages:
1597-1606
Publication date:
2008-06-05
DOI:
EISSN:
1097-0134
ISSN:
0887-3585
URN:
uuid:5990721e-c3ac-4ec1-a4a8-9faa3c08f942
Source identifiers:
100217
Local pid:
pubs:100217

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP