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The relevance in adults of air-flow obstruction, but not of mucus hypersecretion, to mortality from chronic lung disease. Results from 20 years of prospective observation.

Abstract:

From 1954 to 1961, pulmonary function was assessed in 2,718 British men by forced expiratory maneuvers, and mucus hypersecretion and smoking habits were assessed by questionnaires. In 20 to 25 yr of follow-up, 104 men (all of whom had smoked) died of chronic obstructive pulmonary disease (COPD). The risk of death from COPD was strongly correlated with the initial degree of air-flow obstruction. Among men with similar initial air-flow obstruction, however, age-specific COPD death rates were no...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Speizer, FE More by this author
Cochrane, AL More by this author
Fletcher, CM More by this author
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Journal:
The American review of respiratory disease
Volume:
128
Issue:
3
Pages:
491-500
Publication date:
1983-09-05
ISSN:
0003-0805
URN:
uuid:598bc9cc-413a-4774-b773-13f3932717c8
Source identifiers:
42248
Local pid:
pubs:42248

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