ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization.

Journal article

Vaccine research is a combinatorial science requiring computational analysis of vaccine components, formulations and optimization. We have developed a framework that combines computational tools for the study of immune function and vaccine development. This framework, named ImmunoGrid combines conceptual models of the immune system, models of antigen processing and presentation, system-level models of the immune system, Grid computing, and database technology to facilitate discovery, formulat...

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Authors: Pappalardo, F; Halling-Brown, MD; Rapin, N; Zhang, P; Alemani, D

• Publication status: Published
• Journal: Briefings in bioinformatics
• Volume: 10
• Issue: 3
• Pages: 330-340
• Publication date: 2009-05-01
• DOI: 10.1093/bib/bbp014
• EISSN: 1477-4054
• ISSN: 1467-5463
• Language: English
• Keywords: Systems Integration; Drug Design; Humans; Computer Systems; Models, Biological; Database Management Systems; Immune System; Databases, Factual; Major Histocompatibility Complex; Computational Biology; Vaccines