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Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Abstract:

OBJECTIVE:To determine whether serum magnesium and calcium concentrations are causally associated with ischemic stroke or any of its subtypes using the mendelian randomization approach. METHODS:Analyses were conducted using summary statistics data for 13 single-nucleotide polymorphisms robustly associated with serum magnesium (n = 6) or serum calcium (n = 7) concentrations. The corresponding data for ischemic stroke were obtained from the MEGASTROKE consortium (34,217 cases and 404,630 noncas...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1212/WNL.0000000000007001

Authors


Publisher:
American Academy of Neurology
Journal:
Neurology More from this journal
Volume:
92
Issue:
9
Pages:
e944-e950
Publication date:
2019-01-25
Acceptance date:
2018-10-24
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
Pmid:
30804065
Language:
English
Pubs id:
pubs:999381
UUID:
uuid:59776e4d-9724-4080-8a51-b841f6922511
Local pid:
pubs:999381
Source identifiers:
999381
Deposit date:
2019-08-27

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