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DNA probes in human disease.

Abstract:

Nucleic acid probes are able to detect the presence of particular sequences in a sample down to the level of a few hundred molecules. They can discriminate between similar sequences to a resolution of better than one part in 10(9). They are capable of detecting inherited defects in tissues where the phenotype is not being expressed, and in cases where the biochemical aberration is not understood. They can characterize acquired diseases in somatic cells (both tumours and infectious agents). Ad...

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Publication status:
Published

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Authors


Malcolm, AD More by this author
Fallon, RA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Plant Sciences
Figueiredo, H More by this author
Nicholls, PJ More by this author
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Journal:
Biochemical Society symposium
Volume:
53
Issue:
53
Pages:
131-143
Publication date:
1987
EISSN:
1744-1439
ISSN:
0067-8694
URN:
uuid:5966777c-60ed-47fb-89e9-08cd90522305
Source identifiers:
35318
Local pid:
pubs:35318

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