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Reversibility of lymphokine-induced NK-like activity in virus-specific cytotoxic T-lymphocyte clones.

Abstract:

A limiting dilution microculture system, supplemented with a source of interleukin-2 (IL-2), was employed to evaluate the frequency of Moloney-murine leukaemia/sarcoma virus (M-MuLV/M-MSV)-specific cytotoxic T-lymphocyte precursors (CTL-p) which also exhibited NK-like activity. Spleen cells, obtained from M-MuLV/M-MSV regressor mice, were restimulated in bulk secondary mixed leucocyte-tumour cell cultures (MLTC), and subsequently plated in a culture medium supplemented with two different supe...

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Publication status:
Published

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Authors


Ronchese, F More by this author
Collavo, D More by this author
Zanovello, P More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, Biomedical Research Centre
Journal:
Immunology
Volume:
54
Issue:
2
Pages:
265-274
Publication date:
1985-02-05
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:59598137-9bb7-4da5-b77a-c85931b4e619
Source identifiers:
35200
Local pid:
pubs:35200

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