Journal article
Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos.
- Abstract:
-
The Sca-1 surface glycoprotein is used routinely as a marker for haematopoietic stem cell enrichment. Two allelic genes, Ly-6A and Ly-6E, encode this marker and appear to be differentially regulated in haematopoietic cells and haematopoietic stem cells. The Sca-1 protein has been shown to be expressed at a greater frequency in these cells from Ly-6A strains of mice. To study the specific expression pattern and haematopoietic regulation of the Ly-6A gene, we constructed a 14 kb cassette from a...
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Bibliographic Details
- Journal:
- British journal of haematology
- Volume:
- 116
- Issue:
- 2
- Pages:
- 401-408
- Publication date:
- 2002-02-01
- DOI:
- EISSN:
-
1365-2141
- ISSN:
-
0007-1048
- Source identifiers:
-
268137
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:268137
- UUID:
-
uuid:594f51aa-2b93-439a-aef7-4ab354e60669
- Local pid:
- pubs:268137
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2002
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