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Short timescale abnormalities in the states of spontaneous synchrony in the functional neural networks in Alzheimer's disease

Abstract:

Alzheimer's disease (AD) is a prevalent neurodegenerative condition that can lead to severe cognitive and functional deterioration. Functional magnetic resonance imaging (fMRI) revealed abnormalities in AD in intrinsic synchronization between spatially separate regions in the so-called default mode network (DMN) of the brain. To understand the relationship between this disruption in large-scale synchrony and the cognitive impairment in AD, it is critical to determine whether and how the defic...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.nicl.2018.05.028

Authors


Sitnikova, TA More by this author
Hughes, JW More by this author
Ahlfors, SP More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Publisher:
Elsevier Publisher's website
Journal:
NeuroImage: Clinical Journal website
Volume:
20
Pages:
128-152
Publication date:
2018-05-22
Acceptance date:
2018-05-20
DOI:
ISSN:
2213-1582
Pubs id:
pubs:854812
URN:
uri:59408270-ff4d-4c49-8f02-3c292c66dbfd
UUID:
uuid:59408270-ff4d-4c49-8f02-3c292c66dbfd
Local pid:
pubs:854812

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