Journal article icon

Journal article

A model for pathogen population structure with cross-protection depending on the extent of overlap in antigenic variant repertoires.

Abstract:

The persistence of discrete antigenic types among pathogens with multiple immunogenic loci can be explained by the action of immune-mediated competition. It has previously been shown that pathogen populations will self-organize into non-overlapping subsets of antigenic variants if cross-protection between pathogen types sharing any variants is high. Here, we examine the critical question of whether such strain structure will emerge if the degree of immune-mediated competition is dependent on ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.jtbi.2004.08.026

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Journal:
Journal of theoretical biology
Volume:
232
Issue:
3
Pages:
363-373
Publication date:
2005-02-05
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
URN:
uuid:593d49ed-312f-4413-a11f-a0ac3ccd3814
Source identifiers:
209401
Local pid:
pubs:209401

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP