- Abstract:
-
Cytosolic [Ca2+] was measured in single osteoclasts using fura-2 in experiments investigating the effects of Ca2+ "receptor" activation using thapsigargin as a means of depleting intracellular Ca2+ stores. Application of 4 microM thapsigargin to osteoclasts in Ca(2+)-free solutions resulted in an elevation of cytosolic [Ca2+]. Under similar conditions, activation of the osteoclast Ca2+ receptor by the substitute divalent cation agonist, Ni2+, resulted in a transient elevation of cytosolic [Ca...
Expand abstract - Publisher copy:
- 10.1002/jbmr.5650080809
-
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- Journal:
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- Volume:
- 8
- Issue:
- 8
- Pages:
- 961-967
- Publication date:
- 1993-08-05
- DOI:
- EISSN:
-
1523-4681
- ISSN:
-
0884-0431
- URN:
-
uuid:5920ba2d-14ae-4b14-ada9-81971004ffcf
- Source identifiers:
-
475720
- Local pid:
- pubs:475720
- Language:
- English
- Keywords:
- Copyright date:
- 1993
Journal article
Linkage of extracellular and intracellular control of cytosolic Ca2+ in rat osteoclasts in the presence of thapsigargin.
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