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Journal article

Ion channel gates: comparative analysis of energy barriers.

Abstract:

The energetic profile of an ion translated along the axis of an ion channel should reveal whether the structure corresponds to a functionally open or closed state of the channel. In this study, we explore the combined use of Poisson-Boltzmann electrostatic calculations and evaluation of van der Waals interactions between ion and pore to provide an initial appraisal of the gating state of a channel. This approach is exemplified by its application to the bacterial inward rectifier potassium cha...

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Publication status:
Published

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Publisher copy:
10.1007/s00249-008-0377-x

Authors


Journal:
European biophysics journal : EBJ
Volume:
38
Issue:
4
Pages:
347-354
Publication date:
2009-04-05
DOI:
EISSN:
1432-1017
ISSN:
0175-7571
URN:
uuid:591ddae2-e36c-487a-9851-d8536100652b
Source identifiers:
100907
Local pid:
pubs:100907

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