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Journal article

Cerebrospinal fluid/serum gradient of IgG is associated with disability at acute attacks of neuromyelitis optica.

Abstract:

Increased blood-brain barrier (BBB) disruption can be found in patients with neuromyelitis optica (NMO); however, its clinical implication and association with disability at acute attack remains obscure. The purpose of the study was to evaluate the clinical significance of BBB disruption and the subsequent cerebrospinal fluid (CSF)/serum IgG gradient in NMO. Retrospective analysis was made of acute-stage CSF samples from NMO (n = 40) and multiple sclerosis (MS; n = 26) patients. The CSF/serum...

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Publication status:
Published

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Publisher copy:
10.1007/s00415-011-6086-x

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of neurology More from this journal
Volume:
258
Issue:
12
Pages:
2176-2180
Publication date:
2011-12-01
DOI:
EISSN:
1432-1459
ISSN:
0340-5354
Language:
English
Keywords:
Pubs id:
pubs:244066
UUID:
uuid:590fddbf-ef53-47b9-b164-4f71155d798c
Local pid:
pubs:244066
Source identifiers:
244066
Deposit date:
2012-12-19

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