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Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial.

Abstract:

BACKGROUND: In the non-curative setting, the sequence in which anticancer agents are used, singly or in combination, may be important if patients are to receive the maximum period of disease control with the minimum of adverse effects. We compared sequential and combination chemotherapy strategies in patients with unpretreated advanced or metastatic colorectal cancer, who were regarded as not potentially curable irrespective of response. METHODS: We studied patients with advanced colorectal c...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
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Journal:
Lancet
Volume:
370
Issue:
9582
Pages:
143-152
Publication date:
2007-07-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:58f6bd6b-3691-4b38-8076-8dde5da25c3d
Source identifiers:
231641
Local pid:
pubs:231641

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