Brain perfusion follow-up in Alzheimer's patients during treatment with acetylcholinesterase inhibitors.

Journal article

UNLABELLED: Transient cognitive and behavioral stabilization of patients with Alzheimer's disease (AD) is the main goal of long-term acetylcholinesterase inhibitor (AChEI) therapy, but response to treatment is variable and, indeed, only some of the patients are stabilized. This is usually assessed by means of clinical and neuropsychologic scales, whereas functional neuroimaging could allow objective evaluation of the topographic correlates of the effect of therapy on brain functioning. The a...

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Authors: Nobili, F; Koulibaly, M; Vitali, P; Migneco, O; Mariani, G

• Publication status: Published
• Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
• Volume: 43
• Issue: 8
• Pages: 983-990
• Publication date: 2002-08-01
• EISSN: 1535-5667
• ISSN: 0161-5505
• Language: English
• Keywords: Tomography, Emission-Computed, Single-Photon; Carbamates; Brain; Cognition; Alzheimer Disease; Male; Phenylcarbamates; Technetium Tc 99m Exametazime; Cholinesterase Inhibitors; Indans; Aged; Piperidines; Cerebrovascular Circulation; Case-Control Studies; Time Factors; Female; Radiopharmaceuticals; Humans; Follow-Up Studies