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Nanomedicine for the prevention, treatment and imaging of atherosclerosis

Abstract:

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in developed countries, with an increasing prevalence due to an aging population. The pathology underpinning CVD is atherosclerosis, a chronic inflammatory state involving the arterial wall. Accumulation of low density lipoprotein (LDL) laden macrophages in the arterial wall and their subsequent transformation into foam cells lead to atherosclerotic plaque formation. Progression of atherosclerotic lesions may gradual...

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Publisher copy:
10.1016/j.nano.2012.05.006

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Nanomedicine: Nanotechnology, Biology, and Medicine
Volume:
8
Issue:
SUPPL. 1
Publication date:
2012-09-01
DOI:
EISSN:
1549-9642
ISSN:
1549-9634
Source identifiers:
351102
Language:
English
Keywords:
Pubs id:
pubs:351102
UUID:
uuid:58da6d97-b3d9-4638-be89-b9acd843e8a9
Local pid:
pubs:351102
Deposit date:
2013-11-16

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