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Development of an early brain metastasis geometric model for Geant4-DNA simulation

Abstract:

Brain metastases develops frequently in patients with lung and breast cancers, however treatment is mainly palliative and commonly comprises whole-brain irradiation. The pressing therapeutic challenge presented by brain metastases is the need to treat the whole brain in a molecularly targeted manner at an early stage when relatively few metastatic tumour cells have invaded the brain parenchyma. The aim of this preliminary study is to develop a geometric model of early brain metastasis to eval...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1007/s00259-016-3484-4

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Corroyer-Dulmont, A More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
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Publisher:
Springer Publisher's website
Volume:
43
Pages:
S175
Publication date:
2016-09-21
Acceptance date:
2016-06-13
DOI:
EISSN:
1619-7089
ISSN:
1619-7070
Pubs id:
pubs:718623
URN:
uri:58a47012-d09b-4af7-91a7-b994284a351e
UUID:
uuid:58a47012-d09b-4af7-91a7-b994284a351e
Local pid:
pubs:718623

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