- Abstract:
-
The KIAA0319 gene in chromosome 6p22 has been strongly associated with developmental dyslexia. In this article we show a wide expression pattern of this gene in human adult brain by Northern blot analysis. We also performed RT-PCR analysis to detect alternative splicing variants in human brain. Most of the detected variants involve alternative splicing of the exons at the 5' and the 3' ends. Two main forms differing in the length of the 5' UTR are detected at approximately the same rate. Two ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s00335-007-9051-3
-
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- Journal:
- Mammalian genome : official journal of the International Mammalian Genome Society
- Volume:
- 18
- Issue:
- 9
- Pages:
- 627-634
- Publication date:
- 2007-09-05
- DOI:
- EISSN:
-
1432-1777
- ISSN:
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0938-8990
- URN:
-
uuid:58a2eef5-eed1-426a-85db-7851606a0757
- Source identifiers:
-
33970
- Local pid:
- pubs:33970
- Copyright date:
- 2007
Journal article
Alternative splicing in the dyslexia-associated gene KIAA0319.
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