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Journal article

Alternative splicing in the dyslexia-associated gene KIAA0319.

Abstract:

The KIAA0319 gene in chromosome 6p22 has been strongly associated with developmental dyslexia. In this article we show a wide expression pattern of this gene in human adult brain by Northern blot analysis. We also performed RT-PCR analysis to detect alternative splicing variants in human brain. Most of the detected variants involve alternative splicing of the exons at the 5' and the 3' ends. Two main forms differing in the length of the 5' UTR are detected at approximately the same rate. Two ...

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Publication status:
Published

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Publisher copy:
10.1007/s00335-007-9051-3

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Mammalian genome : official journal of the International Mammalian Genome Society
Volume:
18
Issue:
9
Pages:
627-634
Publication date:
2007-09-01
DOI:
EISSN:
1432-1777
ISSN:
0938-8990
Source identifiers:
33970
Language:
English
Keywords:
Pubs id:
pubs:33970
UUID:
uuid:58a2eef5-eed1-426a-85db-7851606a0757
Local pid:
pubs:33970
Deposit date:
2012-12-19

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