Journal article icon

Journal article

Alternative splicing in the dyslexia-associated gene KIAA0319.

Abstract:

The KIAA0319 gene in chromosome 6p22 has been strongly associated with developmental dyslexia. In this article we show a wide expression pattern of this gene in human adult brain by Northern blot analysis. We also performed RT-PCR analysis to detect alternative splicing variants in human brain. Most of the detected variants involve alternative splicing of the exons at the 5' and the 3' ends. Two main forms differing in the length of the 5' UTR are detected at approximately the same rate. Two ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s00335-007-9051-3

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Journal:
Mammalian genome : official journal of the International Mammalian Genome Society
Volume:
18
Issue:
9
Pages:
627-634
Publication date:
2007-09-05
DOI:
EISSN:
1432-1777
ISSN:
0938-8990
URN:
uuid:58a2eef5-eed1-426a-85db-7851606a0757
Source identifiers:
33970
Local pid:
pubs:33970

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP