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Metabolic inflexibility is an early marker of bed-rest-induced glucose intolerance even when fat mass Is stable

Abstract:

Context:The effects of energy-balanced bed rest on metabolic flexibility have not been thoroughly examined. Objective:We investigated the effects of 21 days of bed rest, with and without whey protein supplementation, on metabolic flexibility while maintaining energy balance. We hypothesized that protein supplementation mitigates metabolic inflexibility by preventing muscle atrophy. Design and Setting: Randomized crossover longitudinal study conducted at the German Aerospace Center, Cologne,...

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Publication status:
Published

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Publisher copy:
10.1210/jc.2017-02267

Authors


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Role:
Author
ORCID:
0000-0002-8228-1488
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Role:
Author
ORCID:
0000-0002-3042-7801
Publisher:
Oxford University Press
Journal:
Journal of Clinical Endocrinology and Metabolism More from this journal
Volume:
103
Issue:
5
Pages:
1910-1920
Place of publication:
United States
Publication date:
2018-03-12
Acceptance date:
2018-03-07
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Pmid:
29546280

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