- Abstract:
- There is a necessity to better characterize uveal melanoma (UM) tumors according to their metastasis potential at an early stage. In this study we report the identification of potential biomarkers by a combination of proteomics-related approaches: the characterization of UM cell secretomes, the analysis of UM autoantibodies, and the differential depleted serum proteome analysis. We describe a possible role of cathepsin D, syntenin, and gp100 in UM as potential biomarkers.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1021/pr070021t
-
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- Publisher:
- American Society for Biochemistry and Molecular Biology Publisher's website
- Journal:
- Journal of Proteome Research Journal website
- Volume:
- 6
- Issue:
- 7
- Pages:
- 2802-2811
- Publication date:
- 2006-12-23
- DOI:
- EISSN:
-
1535-3907
- ISSN:
-
1535-3893
- URN:
-
uuid:584a9cce-e1bc-4f7e-beb6-1995f5daf826
- Source identifiers:
-
100277
- Local pid:
- pubs:100277
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2006
- Notes:
- © 2007 American Chemical Society. The final version is available online from the American Chemical Society at: [10.1021/pr070021t]
Journal article
Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum.
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Oxford Glycobiology Institute Endowment
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