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Study protocol: Using deep brain stimulation, multimodal neuroimaging and neuroethics to understand and treat severe enduring Anorexia Nervosa

Abstract:
Background: Research suggests that altered eating and the pursuit of thinness in Anorexia Nervosa is, in part, a consequence of aberrant reward circuitry. The neural circuits involved in reward processing and compulsivity overlap significantly and this has been suggested as a transdiagnostic factor underpinning obsessive compulsive disorder, addictions and eating disorders. The nucleus accumbens is central to both reward processing and compulsivity. In previous studies, deep ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3389/fpsyt.2018.00024

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Oxford college:
Keble College
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Grant:
Concept award awarded to RJP
Charles Wolfson Charitable Trust More from this funder
Swiss Anorexia Foundation More from this funder
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Psychiatry Journal website
Volume:
9
Pages:
Article: 24
Publication date:
2018-04-06
Acceptance date:
2018-01-22
DOI:
ISSN:
1664-0640
Pubs id:
pubs:820955
URN:
uri:582e9450-205e-45c3-8522-d330bc0db683
UUID:
uuid:582e9450-205e-45c3-8522-d330bc0db683
Local pid:
pubs:820955

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