Background: Artemisinin-based combination therapies (ACTs) are the mainstay of the current treatment of uncomplicated P.falciparum malaria, but ACT resistance is spreading across Southeast Asia. Dihydroartemisinin-piperaquine is one of the five ACTs currently recommended by the World Health Organization. Previous studies suggest that young children (<5 years) with malaria are under-dosed. The aim of the following study utilised a population-based pharmacokinetic approach to optimise the an...Expand abstract
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- Hoglund et al.
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- © 2017 Hoglund et al. This is an open access article distributed under the terms of the Creative Commons Attribution License.
Population pharmacokinetic properties of Piperaquine in Falciparum Malaria: an individual participant data-level meta-analysis
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