Journal article icon

Journal article

An efficient asymmetric synthesis of (-)-lupinine.

Abstract:
The asymmetric synthesis of (-)-lupinine was achieved in 8 steps, 15% overall yield and >99 : 1 dr from commercially available starting materials. The strategy used for the construction of the quinolizidine scaffold involved reaction of an enantiopure tertiary dibenzylamine via two sequential ring-closures which both occurred with concomitant N-debenzylation.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1039/c4cc02135e

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Expand authors...
Publisher:
Royal Society of Chemistry
Journal:
Chemical communications (Cambridge, England)
Volume:
50
Issue:
61
Pages:
8309-8311
Publication date:
2014-08-05
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
URN:
uuid:57f73666-38a4-4ec8-a5b5-e09a6f238d2d
Source identifiers:
471119
Local pid:
pubs:471119
Language:
English

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP