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Journal article

Ivermectin for COVID-19 in adults in the community (PRINCIPLE): an open, randomised, controlled, adaptive platform trial of short- and longer-term outcomes

Abstract:
Background
The evidence for whether ivermectin impacts recovery, hospital admissions, and longer-term outcomes in COVID-19 is contested. The WHO recommends its use only in the context of clinical trials.
Methods
In this multicentre, open-label, multi-arm, adaptive platform randomised controlled trial, we included participants aged ≥18 years in the community, with a positive SARS-CoV-2 test, and symptoms lasting ≤14 days. Participants were randomi... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jinf.2024.106130

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-2963-4491
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author

Contributors

Publisher:
Elsevier
Journal:
Journal of Infection More from this journal
Volume:
88
Issue:
4
Article number:
106130
Place of publication:
England
Publication date:
2024-02-29
Acceptance date:
2024-02-22
DOI:
EISSN:
1532-2742
ISSN:
0163-4453
Pmid:
38431155
Language:
English
Keywords:
Pubs id:
1681444
Local pid:
pubs:1681444
Deposit date:
2024-03-20

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