Journal article icon

Journal article

Transplantation of mouse pancreatic islets into primates--in vivo and in vitro evaluation.

Abstract:

BACKGROUND: Islets transplanted from other species to man has the potential to cure diabetes but whether islets are subject to hyperacute rejection after xenotransplantation is contentious. We transplanted mouse pancreatic islets of mouse beneath the primate renal capsule and assessed natural xenoantibody binding, complement activation and cell lysis in vitro. METHODS: Freshly isolated mouse islets were transplanted in a blood clot under the renal capsule of cynolmogus monkeys. The graft was ...

Expand abstract

Actions


Access Document


Authors


McShane, P More by this author
Expand authors...
Journal:
Transplantation
Volume:
72
Issue:
12
Pages:
1867-1874
Publication date:
2001-12-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:57d345bd-cfb9-485c-a7c7-e06d2c5e8608
Source identifiers:
140896
Local pid:
pubs:140896

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP