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Patients with stable long-standing rheumatoid arthritis continue to deteriorate despite intensified treatment with traditional disease modifying anti-rheumatic drugs--results of the British Rheumatoid Outcome Study Group randomized controlled clinical trial.

Abstract:

OBJECTIVE: Patients with rheumatoid arthritis (RA) should start treatment early with the aim of suppressing the inflammatory process completely. It is not known if this strategy should, or can, be continued in later disease. METHODS: In a multicentre, randomized, observer-blinded, controlled trial, 466 patients with established RA (>5 yr), on stable therapy for at least 6 months, were randomized to adequate symptom control/shared care setting (SCSC) or aggressive treatment/hospital settin...

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Publication status:
Published

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Publisher copy:
10.1093/rheumatology/kei169

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Journal:
Rheumatology (Oxford, England)
Volume:
45
Issue:
5
Pages:
558-565
Publication date:
2006-05-05
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
URN:
uuid:57c4ae57-0899-4781-9dd7-645773c88ed1
Source identifiers:
144340
Local pid:
pubs:144340

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