Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.

Eggermont, J; Proudfoot, NJ

Abstract:

Transcriptional termination by RNA polymerase II at the 3' end of genes encoding poly(A)+ mRNAs is thought to require two distinct cis-active elements: a functional poly(A) signal and a downstream transcriptional pause site. An important requirement for efficient termination is to prevent transcriptional interference of downstream-located promoters. We have therefore investigated whether these two elements, individually or in combination, can prevent transcriptional interference of RNA polyme...

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Publication status:

Published

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APA Style

Eggermont, J., & Proudfoot, N. J. (1993). Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters. The EMBO Journal, 12(6), 2539–2548.

MLA Style

Eggermont, J., and N. J. Proudfoot. “Poly(A) Signals and Transcriptional Pause Sites Combine to Prevent Interference between RNA Polymerase II Promoters.” The EMBO Journal, vol. 12, no. 6, 1993, pp. 2539–48.

Chicago Style

Eggermont, J, and NJ Proudfoot. 1993. “Poly(A) Signals and Transcriptional Pause Sites Combine to Prevent Interference between RNA Polymerase II Promoters.” The EMBO Journal 12 (6): 2539–48.
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