Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters. - ORA - Oxford University Research Archive

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Journal article

Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.

Abstract:: Transcriptional termination by RNA polymerase II at the 3' end of genes encoding poly(A)+ mRNAs is thought to require two distinct cis-active elements: a functional poly(A) signal and a downstream transcriptional pause site. An important requirement for efficient termination is to prevent transcriptional interference of downstream-located promoters. We have therefore investigated whether these two elements, individually or in combination, can prevent transcriptional interference of RNA polyme...
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Publication status:: Published

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APA Style

Eggermont, J., & Proudfoot, N. (2016). Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters. EMBO Journal, 12(6), 2539–2548.

MLA Style

Eggermont, J., and N. Proudfoot. “Poly(A) Signals and Transcriptional Pause Sites Combine to Prevent Interference between RNA Polymerase II Promoters.” EMBO Journal, vol. 12, no. 6, 2016, pp. 2539–48.

Chicago Style

Eggermont, J, and N Proudfoot. 2016. “Poly(A) Signals and Transcriptional Pause Sites Combine to Prevent Interference between RNA Polymerase II Promoters.” EMBO Journal 12 (6): 2539–48.
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Authors

+ Eggermont, J More by this author

Role:

Author

+ Proudfoot, N More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Pathology Dunn School

Role:

Author

Bibliographic Details

Journal:: EMBO journal
Volume:: 12
Issue:: 6
Pages:: 2539-2548
Publication date:: 1993-06-01
EISSN:: 1460-2075
ISSN:: 0261-4189
Source identifiers:: 7305

Item Description

Language:: English
Keywords:: RNA Polymerase II

Terminator Regions, Genetic

Humans

Plasmids

HIV Long Terminal Repeat

HIV-1

Poly A

Hela Cells

Promoter Regions, Genetic
Pubs id:: pubs:7305
UUID:: uuid:57bca2ae-cbae-40a7-b4ec-d4f2689fec46
Local pid:: pubs:7305
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 1993

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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