OBJECTIVES: This study sought to determine the effects of a p38 mitogen-activated protein kinase inhibitor, losmapimod, on vascular inflammation, by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography imaging. BACKGROUND: The p38 mitogen-activated protein kinase cascade plays an important role in the initiation and progression of inflammatory diseases, including atherosclerosis. METHODS: Patients with atherosclerosis on stable statin therapy (n = 99) were randomize...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Effects of p38 mitogen-activated protein kinase inhibition on vascular and systemic inflammation in patients with atherosclerosis.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record