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Detrimental effect of eicosapentaenoic acid supplementation on bone following ovariectomy in rats.

Abstract:

Although several studies have reported a positive effect of n-3 essential fatty acids (EFAs) on bone density post-ovariectomy, the role of specific EFAs has yet to be fully elucidated. In this study, ovariectomised (OVX) rats were supplemented with 0.1 g (LOW) or 1.0 g (HIGH) of eicosapentaenoic acid (EPA)/kg body weight for 9 weeks. Bone mineral density (BMD), 25-hydroxyvitamin D(3) and plasma fatty acid profile were compared to those of OVX and sham animals fed a non-supplemented diet. BMD ...

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Publication status:
Published

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Publisher copy:
10.1016/j.plefa.2006.08.003

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Journal:
Prostaglandins, leukotrienes, and essential fatty acids
Volume:
75
Issue:
6
Pages:
419-427
Publication date:
2006-12-05
DOI:
EISSN:
1532-2823
ISSN:
0952-3278
URN:
uuid:5781b4f6-7fcd-4de4-bfe0-6b46fd1fbe88
Source identifiers:
229520
Local pid:
pubs:229520

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