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Journal article

Combinatorial protein recognition as an alternative approach to antibody-mimetics.

Abstract:

Current approaches to medical diagnostics and drug design are largely based on the ability of monoclonal antibodies or synthetic molecules to bind proteins with high affinity and selectivity. In recent years, however, an alternative approach to protein recognition has emerged, in which proteins are identified using non-specific receptor arrays that are inspired by the olfactory neural system. An ultimate challenge for such systems is realizing a single, high-throughput analytical device that ...

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Publication status:
Published

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Publisher copy:
10.1016/j.cbpa.2010.07.017

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
Current opinion in chemical biology
Volume:
14
Issue:
6
Pages:
705-712
Publication date:
2010-12-05
DOI:
EISSN:
1879-0402
ISSN:
1367-5931
URN:
uuid:577fe3b5-869b-4a28-8b78-463b9136ce64
Source identifiers:
118090
Local pid:
pubs:118090

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