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Isolation of DNTR polymorphisms from yeast artificial chromosomes encompassing X chromosomal loci PGK1 and DXS56.

Abstract:

Five dinucleotide tandem repeat (DNTR) sequences were isolated from yeast artificial chromosomes containing the PGK1 and DXS56 loci in Xq13. Sequence information of these DNTR loci is given. Four of the five DNTR sequences were polymorphic. Polymorphism information content values were 0.44, 0.49, 0.47, and 0.76 for loci PY5-10, PY2-31, 4548-1, and 4548-7, respectively. Corresponding heterozygosities were 0.55, 0.55, 0.56, and 0.78. These DNTRs are useful for the fine mapping of disease loci i...

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Publication status:
Published

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Publisher copy:
10.1007/bf00220077

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Journal:
Human genetics
Volume:
90
Issue:
3
Pages:
270-274
Publication date:
1992-11-05
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
URN:
uuid:57615283-3396-4195-b42e-bd9cddfbe5c9
Source identifiers:
43935
Local pid:
pubs:43935

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