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Journal article

Specific proliferative T cell responses and antibodies elicited by vaccination with simian immunodeficiency virus Nef do not confer protection against virus challenge.

Abstract:

The efficacy of immunizing with a combination of simian immunodeficiency virus (SIV) Nef vaccines was evaluated. Four vaccinates received three intradermal immunizations with recombinant vaccinia virus that expressed SIV Nef, followed by three intramuscular immunizations with rDNA also expressing SIV Nef. Finally, the four vaccinates received two subcutaneous boosts with recombinant SIV Nef protein. This immunization protocol elicited anti-Nef antibodies in all of the vaccinates as well as sp...

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Publication status:
Published

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Publisher copy:
10.1089/08892220152644223

Authors


Wade-Evans, AM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Stebbings, R More by this author
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Journal:
AIDS research and human retroviruses
Volume:
17
Issue:
16
Pages:
1517-1526
Publication date:
2001-11-05
DOI:
EISSN:
1931-8405
ISSN:
0889-2229
URN:
uuid:574cb5ba-e8c5-45fe-8562-3a9ca5365726
Source identifiers:
67022
Local pid:
pubs:67022

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