- Abstract:
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AIMS: Endothelin-1 (ET-1) has been shown to increase endothelial superoxide (O(2)(-)) production in experimental animal models. It is unclear whether ET-1 increases O(2)(-) production in humans. We sought to elucidate whether ET-1 increases O(2)(-) production in human vessels and to identify the mechanism behind this effect. MAIN METHODS: Segments of internal mammary artery (IMA) and human saphenous vein (HSV) were harvested from 90 patients undergoing elective coronary artery bypass graft su...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.lfs.2012.03.024
-
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- Volume:
- 91
- Issue:
- 13-14
- Pages:
- 723-728
- Publication date:
- 2012-10-05
- DOI:
- EISSN:
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1879-0631
- ISSN:
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0024-3205
- URN:
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uuid:573f6e6f-dd4c-4c48-83a1-5da3c3e4699a
- Source identifiers:
-
132199
- Local pid:
- pubs:132199
- Keywords:
- Copyright date:
- 2012
Conference
Endothelin-1 increases superoxide production in human coronary artery bypass grafts.
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