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PPARs and adipocyte function.

Abstract:

For long viewed as passive lipid storage depots, adipocytes are now recognised as key players in the pathogenesis of insulin resistance and metabolic disease. In parallel, the last two decades of research have seen the emergence of transcription factors of the peroxisome proliferator-activated receptor (PPAR) family as central regulators of lipid and glucose homeostasis and molecular targets for drugs to treat hyper-lipidaemia and type 2 diabetes mellitus. In this review we discuss the charac...

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Publication status:
Published

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Publisher copy:
10.1016/j.mce.2009.09.014

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
Journal:
Molecular and cellular endocrinology
Volume:
318
Issue:
1-2
Pages:
61-68
Publication date:
2010-04-05
DOI:
EISSN:
1872-8057
ISSN:
0303-7207
URN:
uuid:572d9a53-6137-4d5a-80e3-a40e7d364fee
Source identifiers:
149979
Local pid:
pubs:149979

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